Search Results - foreign+body+response

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Biopanned peptides targeting glial phenotypes in ramified, primed, and activated brain microglia and astrocytes

NU 2022-114 SHORT DESCRIPTION Northwestern and University of Alberta researchers have developed a phage display selection method that identifies peptides binding microglia and astrocytes according to their inflammatory activation state, along with 58 peptide ligands discovered and validated using it. BACKGROUND Neuroinflammation is a shared component...

Published: 8/6/2026 | Updated: 8/6/2026 | Inventor(s):

Keywords(s): AD - Alzheimer’s Disease, BIO2026, Biomarker, CNS - Central Nervous System, CVA - Cerebrovascular Accident, Enabling technology, Foreign body response, Implantable devices, Inflammation, Neurodegenerative disease, Neurologic disease

Category(s): Life Sciences > Therapeutics, Life Sciences, Life Sciences > Biomarkers & Biomedical Research Tools

Self-assembling peptides with hyaluronic acid binding domains to form hydrogels

NU 2022-016 INVENTORS Kyle M. Koss Terrance J. Sereda* Jason A. Wertheim* ABSTRACT A new class of self-assembling peptides with hyaluronic acid-binding domains shows great promise for biomedical applications, particularly in treating injuries, cancer, and enhancing the function of implantable devices. These peptides self-assemble into nanofibers...

Published: 12/11/2025 | Updated: 9/10/2024 | Inventor(s):

Keywords(s): Cancer/Oncology, Drug delivery, Enabling technology, Foreign body response, Implantable devices, Inflammation, Lung disease, Wound healing

Category(s): Life Sciences > Therapeutics