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Bioactive Supramolecular Peptide Amphiphile Platforms for CNS In Vitro Models, CNS Regeneration, and Neurotherapeutic Delivery
SHORT DESCRIPTION
A suite of self‑assembling peptide amphiphile nanostructures and hydrogels that mimic key neurotrophic factors, modulate ionic and electrical microenvironments, and protect therapeutic peptides to enhance neural survival, maturation, and regeneration across CNS diseases and injuries
INVENTORS
Samuel I Stupp
Weinberg...
Published: 6/16/2026
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Updated: 6/16/2026
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Inventor(s):
Keywords(s): AD - Alzheimer’s Disease, ALS - Amyotrophic Lateral Sclerosis, BIO2026, Biomaterials, CNS - Central Nervous System, Drug delivery, Drug discovery, Drug screening, Hydrogel, In vitro models, Neurology, PD - Parkinson's Disease, Regenerative medicine, Research tool, Scaffold, SCI - Spinal cord injury, Smart/Functional materials, Therapeutics
Category(s): Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics
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Photo-expanding Spiropyran Hydrogels
yle>
2021-037
Short Description
Sulfonate-based, water-soluble spiropyran photoswitches can be covalently incorporated into hydrogel networks to trigger light-driven volumetric expansion, with reversible contraction under dark conditions. The technology enables photoresponsive hydrogels and soft materials with tunable actuation behavior using light,...
Published: 5/18/2026
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Updated: 5/18/2026
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Inventor(s):
Keywords(s): Hydrogel, Materials, Smart/Functional materials
Category(s): Physical Sciences > Materials and Industrial Processes
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Targeted Nanofiber Therapy for Atherosclerosis – Enhanced Plaque Regression via Precise Drug Delivery
SHORT DESCRIPTION
Nanofiber-based drug delivery system that targets atherosclerotic plaque and delivers a therapeutic agent locally to induce plaque regression for management of cardiovascular disease.
INVENTORS
Samuel Stupp*
Weinberg College of Arts and Sciences, Department of Chemistry
* Principal Investigator
NU...
Published: 6/16/2026
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Updated: 4/30/2026
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Inventor(s):
Keywords(s): Atherosclerosis, BIO2026, Biomaterials, Cardiology and Cardiovascular disease, Drug delivery, Nanomaterials, Nanotechnology, Self-assembly, Smart/Functional materials, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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Bioactive, Conductive, and Antioxidant Supramolecular Polymer Hydrogels for Neural Applications
SHORT DESCRIPTION
Biomaterial scaffold for neural cell culture and therapeutic implants that harnesses bioactive, conductive, and antioxidant properties to boost neural cell viability and maturation.
INVENTORS
Samuel Stupp*
Weinberg College of Arts and Sciences, Department of Chemistry
Anna Metlushko
Bo...
Published: 6/16/2026
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Updated: 4/30/2026
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Inventor(s):
Keywords(s): BIO2026, Biologic, Biomaterials, CNS - Central Nervous System, Implantable devices, Neurology, Regenerative medicine, Scaffold, SCI - Spinal cord injury, Smart/Functional materials
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT > Neurology, Life Sciences > Therapeutics
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Novel self-healing commodity copolymers based on 2-ethylhexyl acrylate
NU2023-240
INVENTORS
John Torkelson*
Tong Wang
SHORT DESCRIPTION
This invention describes a new class of random copolymers that exhibit autonomous self-healing behavior at room temperature. The copolymers, derived entirely from commodity comonomers including 2-ethylhexyl acrylate, fully recover their material properties after damage.
BACKGROUND
The...
Published: 11/6/2025
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Updated: 7/30/2025
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Inventor(s):
Keywords(s): Materials, Polymer, Smart/Functional materials
Category(s): Physical Sciences > Materials and Industrial Processes
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A Flexible, Architected Soft Robotic Actuator for Linear, Servo-Driven Motion
A Flexible, Architected Soft Robotic Actuator for Linear, Servo-Driven Motion
NU 2024-095
INVENTORS
Ryan Truby*
Taekyoung Kim
SHORT DESCRIPTION
This technology introduces a flexible, architected soft robotic actuator designed for linear, servo-driven motion, offering enhanced adaptability and efficiency for various robotic applications.
BACKGROUND
Soft...
Published: 11/6/2025
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Updated: 5/19/2025
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Inventor(s):
Keywords(s): 3D Printing/Additive Manufacturing, Robotics, Smart/Functional materials
Category(s): Physical Sciences > Engineering & Technology, Physical Sciences > Materials and Industrial Processes
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Bioresorbable, wireless, and battery-free electrotherapy system for wound healing and monitoring in diabetes
NU 2022-079
INVENTORS
Guillermo Ameer*
John Rogers*
Joseph Woojin Song
Han Jun Ryu
SHORT DESCRIPTION
A revolutionary bioresorbable, wireless, and battery-free electrotherapy system designed for effective wound healing and monitoring in diabetic patients.
BACKGROUND
Diabetes is a highly prevalent disease, affecting 1 in 3 Americans. Diabetes is associated...
Published: 11/6/2025
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Updated: 5/8/2025
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Inventor(s):
Keywords(s): Diabetes, Electronics & Circuits, Materials, Medical device, Smart/Functional materials
Category(s): Life Sciences > Healthcare Devices, Tools & IT
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Printable Optoelectronic Inks Based on Two-Dimensional Semiconductors
NU 2018-164
INVENTORS
Jung-Woo Ted Seo
Jian Zhu
Mark C. Hersam*
SHORT DESCRIPTION
Preparation of printable semi-conductor inks for fabrication of high-fidelity optoelectronic devices
ABSTRACT
Northwestern researchers have developed an approach to prepare semiconducting inks that enable the fabrication of optoelectronic devices through inkjet...
Published: 11/6/2025
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Updated: 1/26/2023
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Inventor(s):
Keywords(s): Electronics & Circuits, Materials, Semiconductors & Integrated Circuits, Sensors, Smart/Functional materials
Category(s): Physical Sciences > Materials and Industrial Processes, Physical Sciences > Engineering & Technology
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