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Biomimetic HDL Nanoparticles for Treatment of Cancer, Immune and Inflammatory Disorders, and Cardiovascular Disease
SHORT DESCRIPTION
Self-assembling biomimetic high-density lipoprotein nanoparticle (HDL NP) platform technology with a soft organic core, designed to more closely replicate key functional properties of mature human HDL for therapeutic use in cardiovascular disease, cancer, and inflammatory/immune disorders.
INVENTORS
Colby Thaxton*
Northwestern...
Published: 6/16/2026
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Updated: 6/16/2026
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Inventor(s):
Keywords(s): Atherosclerosis, Autoimmune disease, BIO2026, Breast cancer, Cancer/Oncology, Cardiology and Cardiovascular disease, Gene therapy, Immunology, Immunotherapy, Inflammation, Nanomaterials, Nanoparticle, Nanotechnology, Nucleic Acids, Platform technology, Prostate cancer, Research tool, Small molecule, Targeted therapy, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Therapeutics
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Targeted Nanofiber Therapy for Atherosclerosis – Enhanced Plaque Regression via Precise Drug Delivery
SHORT DESCRIPTION
Nanofiber-based drug delivery system that targets atherosclerotic plaque and delivers a therapeutic agent locally to induce plaque regression for management of cardiovascular disease.
INVENTORS
Samuel Stupp*
Weinberg College of Arts and Sciences, Department of Chemistry
* Principal Investigator
NU...
Published: 6/16/2026
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Updated: 4/30/2026
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Inventor(s):
Keywords(s): Atherosclerosis, BIO2026, Biomaterials, Cardiology and Cardiovascular disease, Drug delivery, Nanomaterials, Nanotechnology, Self-assembly, Smart/Functional materials, Targeted therapy, Therapeutics
Category(s): Life Sciences > Therapeutics
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A New Method to Encapsulate Gas in Liposomes for Delivery to Diseased Tissue
NU 2006-048INVENTORSRobert MacDonald*David McPhersonShao-Ling HuangPatrick Kees SHORT DESCRIPTIONA method of producing nitrous oxide-containing liposomes for the treatement of diseaseBACKGROUNDNitrous oxide (NO) gas is a major signalling molecule in many tissues of the body. In the blood vessels, NO regulates bloodflow by increasing vessel diameter....
Published: 11/6/2025
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Updated: 4/24/2020
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Inventor(s):
Keywords(s): Atherosclerosis, Drug delivery
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Novel Method of Enzymatic Plaque Digestion
NU 2008-157 Inventors Guillermo Ameer* Melina Kibbe* Jason Rubenstein Abstract Northwestern investigators have developed a novel plaque digestion composition to remove atherosclerotic plaque with minimal trauma to the arterial wall and minimal risk to the patient. No such approach has ever been utilized in patients. Balloons and mechanical blades...
Published: 11/6/2025
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Updated: 10/27/2018
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Inventor(s):
Keywords(s): Atherosclerosis, Cardiology and Cardiovascular disease, Therapeutics
Category(s): Life Sciences > Therapeutics
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