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Advanced Pulsed-Laser Synthesis for Metal Carbides
NU 2025-190
SHORT DESCRIPTION
A pulsed-laser synthesis method for making advanced metastable materials, including metal carbides and nitrides.
INVENTORS
Bryan Hunter*
Alexis Magana
Christopher Nowak
* Principal Investigator
NU 2025-190
IP STATUS
Provisional Application Filed (joint with Harvard University)
DEVELOPMENT...
Published: 4/10/2026
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Updated: 4/10/2026
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Inventor(s):
Keywords(s): Materials, Metals, Nanoparticle
Category(s): Physical Sciences > Materials and Industrial Processes
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Targeted pH Sensitive Liposomes
NU 2020-170
INVENTORS
Leo Gordon*
Dong-Hyun Kim*
Shuo Yang
Wooram Park
Taehoon Sim
SHORT DESCRIPTION
Liposomal nanoparticles composed of pH-sensitive lipids and apolipoprotein that encapsulate andrographolide for lymphoma treatment.
BACKGROUND
Lymphoma, particularly diffuse large B-cell lymphoma (DLBCL), is the most common aggressive type...
Published: 3/11/2026
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Updated: 3/11/2026
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Inventor(s):
Keywords(s): Blood & Lymphatic disease, Cancer/Oncology, Nanoparticle, Therapeutics
Category(s): Life Sciences > Therapeutics
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Spherical Nucleic Acids with Sheddable PEG Layers for Enhanced Tumor Targeting
NU 2017-169
INVENTORS
Chad Mirkin* (Northwestern University, Weinberg College of Arts and Sciences, Department of Chemistry, Director of the International Institute for Nanotechnology (IIN))
Brian Meckes
Wuliang Zhang
SHORT DESCRIPTION
For oncology applications, this invention offers spherical nucleic acids with an enzyme-cleavable PEG layer...
Published: 12/9/2025
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Updated: 10/30/2025
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Inventor(s):
Keywords(s): Biologic, Biomarker, Biomedical, Cancer/Oncology, Chemicals, Diagnostics, Drug delivery, Nanoparticle, Nanotechnology, Personalized medicine, Therapeutics
Category(s): Life Sciences > Therapeutics, Life Sciences > Healthcare Devices, Tools & IT, Life Sciences > Biomarkers & Biomedical Research Tools
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High-index Facet Nanocatalysts for Clean Energy Applications
NU2023-109
INVENTORS
Chad Mirkin*
Bo Shen
Zihao Ye
SHORT DESCRIPTION
A machine learning-guided, high-throughput DFT approach to synthesize high-index facet nanocatalysts with enhanced catalytic performance and broader material applicability.
BACKGROUND
Nanocrystals with high-index facets offer superior catalytic activity due to their abundance...
Published: 11/6/2025
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Updated: 7/16/2025
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Inventor(s):
Keywords(s): Catalyst, Cleantech, Materials, Metals, Nanomaterials, Nanoparticle
Category(s): Physical Sciences > Engineering & Technology
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Megalibrary Platform for Oxygen Evolution Reaction Catalysts
NU 2023-039
INVENTORS
Chad Mirkin*
Jin Huang
SHORT DESCRIPTION
A high-throughput nanoparticle megalibrary platform for discovering multielemental catalysts with enhanced activity and stability for oxygen evolution reactions in electrochemical energy systems.
BACKGROUND
The oxygen evolution reaction (OER) is a critical reaction in electrochemical...
Published: 11/6/2025
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Updated: 7/16/2025
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Inventor(s):
Keywords(s): Chemicals, Cleantech, Materials, Nanomaterials, Nanoparticle, Spectroscopy
Category(s): Physical Sciences > Materials and Industrial Processes
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Functionalized lipid nanoparticles
NU 2022-184
INVENTORS
Neha Kamat*
Justin Alexander Peruzzi*
Timothy Vu*
SHORT DESCRIPTION
This technology facilitates the rapid expression and conjugation of therapeutic proteins to nanoparticles, creating highly specific drug delivery systems that can be generated swiftly and cost-effectively.
BACKGROUND
In recent years, there...
Published: 4/13/2026
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Updated: 2/28/2025
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Inventor(s):
Keywords(s): Drug delivery, Drug screening, HTS - High-throughput screening, Nanoparticle, Nanotechnology, Research tool, Targeted therapy, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Engineered Lipid Tags for Extracellular Vesicle Loading
NU 2022-178
INVENTORS
Neha Kamat*
Joshua Leonard*
Justin Alexander Peruzzi
Taylor Gunnels
SHORT DESCRIPTION
This technology enhances the loading of protein cargo into extracellular vesicles (EVs) by directing protein association with membrane lipid rafts, utilizing engineered lipid tags for targeted delivery.
BACKGROUND
Extracellular...
Published: 4/13/2026
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Updated: 2/28/2025
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Inventor(s):
Keywords(s): Biotechnology, Drug delivery, Nanomaterials, Nanoparticle, Nanotechnology, Synthetic biology, Targeted therapy, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Leveraging Lipid-Protein Interactions to Engineer Spatial Organization in Cell-free Systems
NU 2021-231
INVENTORS
Neha Kamat*
Justin Alexander Peruzzi
Jan Steinkuehler
SHORT DESCRIPTION
This innovative method enables the control of membrane protein location and distribution in synthetic lipid membranes using lipid-protein interactions, without chemical conjugation, facilitating the development of advanced cell-free systems.
BACKGROUND
Spatially...
Published: 4/9/2026
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Updated: 2/28/2025
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Inventor(s):
Keywords(s): Drug delivery, Nanomaterials, Nanoparticle, Nanotechnology, Research tool, Synthetic biology, Targeted therapy, Therapeutics
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools, Physical Sciences > Engineering & Technology
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Membrane Encapsulation of a Transcriptionally Regulated Cell-Free Biosensor
NU 2022-162
INVENTORS
Neha P. Kamat*
Julius B. Lucks*
Margrethe Boyd
Walter M. Thavarajah
BACKGROUND
Cell-free systems allow biochemical processes traditionally performed by cells to be reproduced independent of cells in a cost-effective, distributable, and highly tunable manner. Specifically, cell-free biosensors have enabled...
Published: 4/13/2026
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Updated: 10/17/2024
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Inventor(s):
Keywords(s): Biosensors, Nanoparticle, Nanotechnology, Synthetic biology
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Assembly of Vaccines Using Cell-Free Integration of Viral Membrane Proteins into Liposomes
NU 2022-192
INVENTORS
Neha P. Kamat*
Vivian Hu
BACKGROUND
Virus infection posts a recurring global health challenge, and vaccines remain an effective protective against virus threats. However, many current vaccines face limitations including potential conversion of inactivated virus into pathogenic virus, immunogenicity of recombinant...
Published: 4/10/2026
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Updated: 10/17/2024
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Inventor(s):
Keywords(s): Immunology, Infectious disease, Nanomaterials, Nanoparticle, Nanotechnology, Synthetic biology, Vaccine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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