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Assembly of Vaccines Using Cell-Free Integration of Viral Membrane Proteins into Liposomes
NU 2022-192
INVENTORS
Neha P. Kamat*
Vivian Hu
BACKGROUND
Virus infection posts a recurring global health challenge, and vaccines remain an effective protective against virus threats. However, many current vaccines face limitations including potential conversion of inactivated virus into pathogenic virus, immunogenicity of recombinant...
Published: 4/10/2026
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Updated: 10/17/2024
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Inventor(s):
Keywords(s): Immunology, Infectious disease, Nanomaterials, Nanoparticle, Nanotechnology, Synthetic biology, Vaccine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Novel Nanocarriers for Improved Vaccine Efficacy and Production
NU 2019-066
INVENTORS
Dina Kats
Shaobin Shang
Chyung-Ru Wang
Evan A. Scott*
SHORT DESCRIPTION
A novel vaccine delivery system for enhanced immune response
BACKGROUND
In contrast to attenuated vaccines that contain live pathogens, subunit vaccines contain peptide antigens from a specific pathogen, enabling them to be produced more quickly...
Published: 4/10/2026
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Updated: 9/11/2020
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Inventor(s):
Keywords(s): COVID-19, Infectious disease, Nanoparticle, Nanotechnology, Therapeutics, Vaccine
Category(s): Life Sciences > Therapeutics
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Compositions and Methods for Solubilizing Membrane Proteins without the Use of Detergent
NU 2009-069 Inventor Adrian Gross*Abstract Northwestern researchers have developed a novel method for isolating integral membrane proteins in a detergent-free manner. This process offers the ability to isolate solubilized membrane complex in its native lipid environment with undisturbed changes in its composition and structure. These attributes...
Published: 11/6/2025
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Updated: 2/8/2019
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Inventor(s):
Keywords(s): Drug delivery, Research reagent, Research tool, Vaccine
Category(s): Life Sciences > Biomarkers & Biomedical Research Tools
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Microbial Modulation of Immunity and Pain
NU 2008-022 Inventors David Klumpp* Anthony Schaeffer* Praveen Thumbikat Short DescriptionAn attenuated-live UTI vaccineAbstract Northwestern researchers have developed therapies to treat urinary tract infection (UTI). They use novel UTI therapeutic approaches by targeting the cell-mediated response instead of the humoral responses, which is the...
Published: 11/6/2025
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Updated: 2/8/2019
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Inventor(s):
Keywords(s): Biomarker, Chronic pain, Therapeutics, Vaccine
Category(s): Life Sciences > Therapeutics
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A Live-Attenuated Vaccine for Urinary Tract and Other Bacterial Infections
NU 2008-004 Inventors Anthony J. Schaeffer*David J. KlumppBenjamin BillipsShort DescriptionA bacterial strain that promotes immune response for UTI treatmentAbstractUrinary tract infections, either chronic or acute, are a frequent health problem in a variety of populations. Northwestern investigators have demonstrated that deletion of a certain gene...
Published: 3/19/2026
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Updated: 2/8/2019
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Inventor(s):
Keywords(s): Immunology, Infectious disease, Therapeutics, Urology, Vaccine
Category(s): Life Sciences > Therapeutics
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New Target for Malaria Therapeutics and Prophylaxis
NU 2007-138 InventorsKasturi Haldar* Pamela Tamez Souvik Bhattacharjee Short DescriptionA new malarial protein that can be targeted to treat and prevent infectionsAbstractNorthwestern researchers have identified a new malarial protein, named erythrocyte vesicle protein 1 (EVP1), which can be targeted for development of drugs and vaccines. Currently,...
Published: 11/6/2025
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Updated: 10/27/2018
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Inventor(s):
Keywords(s): Infectious disease, Therapeutics, Vaccine
Category(s): Life Sciences > Therapeutics
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